ea0063p782 | Thyroid 2 | ECE2019
Boutzios Georgios
, Papaoiconomou Eleni
, Koukoulioti Eleni
, Boronikolos Georgios
, Spartalis Elefterios
, Kykalos Stylianos
, Tsourouflis Gerasimos
Introduction: Previous studies have shown that the G691S and S904S variants of RET proto-oncogene are associated with Multiple Endocrine Neoplasia (MEN) 2A syndrome and have a modifier effect on the age of onset. They are also associated with Papillary Thyroid Carcinoma and with Pheochromocytoma without Medullary Thyroid Carcinoma (MTC). Nevertheless, the influence of these polymorphisms on cases of sporadic MTC is still unclear. We present a patient with sporadic Med...